🔗 Gene Gun

🔗 Genetics 🔗 Molecular Biology/Molecular and Cell Biology

In genetic engineering, a gene gun or biolistic particle delivery system is a device used to deliver exogenous DNA (transgenes), RNA, or protein to cells. By coating particles of a heavy metal with a gene of interest and firing these micro-projectiles into cells using mechanical force, an integration of desired genetic information can be induced into cells. The technique involved with such micro-projectile delivery of DNA is often referred to as biolistics.

This device is able to transform almost any type of cell and is not limited to the transformation of the nucleus; it can also transform organelles, including plastids and mitochondria.