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🔗 Medicine 🔗 Medicine/Pulmonology 🔗 Physiology 🔗 Scuba diving 🔗 Physiology/respiratory

Liquid breathing is a form of respiration in which a normally air-breathing organism breathes an oxygen-rich liquid (such as a perfluorocarbon), rather than breathing air.

This requires certain physical properties such as respiratory gas solubility, density, viscosity, vapor pressure, and lipid solubility which some, but not all, perfluorochemicals (perfluorocarbon) have. Thus, it is critical to choose the appropriate PFC for a specific biomedical application, such as liquid ventilation, drug delivery or blood substitutes. The physical properties of PFC liquids vary substantially; however, the one common property is their high solubility for respiratory gases. In fact, these liquids carry more oxygen and carbon dioxide than blood.

In theory, liquid breathing could assist in the treatment of patients with severe pulmonary or cardiac trauma, especially in pediatric cases. Liquid breathing has also been proposed for use in deep diving and space travel. Despite some recent advances in liquid ventilation, a standard mode of application has not yet been established.

🔗 International relations 🔗 History 🔗 Disaster management 🔗 Medicine 🔗 Viruses 🔗 Lists 🔗 History of Science

This article is a list of deaths caused by an infectious disease. Widespread non-communicable diseases such as cardiovascular disease and cancer are not included.

🔗 Disaster management 🔗 Medicine 🔗 Viruses 🔗 COVID-19 🔗 Medicine/Pulmonology 🔗 Medicine/Emergency medicine and EMS

A COVID-19 vaccine is a hypothetical vaccine against coronavirus disease 2019 (COVID‑19). Although no vaccine has completed clinical trials, there are multiple attempts in progress to develop such a vaccine. In February 2020, the World Health Organization (WHO) said it did not expect a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus, to become available in less than 18 months. The Coalition for Epidemic Preparedness Innovations (CEPI) – which is organizing a US$2 billion worldwide fund for rapid investment and development of vaccine candidates – indicated in April that a vaccine may be available under emergency use protocols in less than 12 months or by early 2021. On 4 May 2020, the WHO organized a telethon to raise US$8 billion from forty countries to support rapid development of vaccines to prevent COVID-19 infections, also announcing deployment of an international "Solidarity trial" for simultaneous evaluation of several vaccine candidates reaching Phase II-III clinical trials.

By May, 159 vaccine candidates were in development, with five having been initiated in Phase I–II safety and efficacy studies in human subjects, and seven in Phase I trials.

🔗 Medicine 🔗 Maine

The Jumping Frenchmen of Maine were a group of 19th-century lumberjacks who exhibited a rare disorder of unknown origin. The syndrome entails an exaggerated startle reflex which may be described as an uncontrollable "jump"; individuals with this condition can exhibit sudden movements in all parts of the body. Jumping Frenchmen syndrome shares some symptoms with other startle disorders.

Individuals with this condition were first found in the Moosehead Lake region of Maine, and were first described by George Miller Beard in 1878.

🔗 United States 🔗 International relations 🔗 Disaster management 🔗 Medicine 🔗 Viruses 🔗 Death

The 2009 flu pandemic in the United States was a novel strain of the Influenza A/H1N1 virus, commonly referred to as "swine flu", that began in the spring of 2009. The virus had spread to the US from an outbreak in Mexico.

The U.S. Centers for Disease Control and Prevention (CDC) estimates that from April 12, 2009 to April 10, 2010, there were 60.8 million cases, 274,000 hospitalizations, and 12,469 deaths (0.02% infection fatality rate/Mortality rate) in the United States due to the virus.

🔗 Medicine 🔗 Death 🔗 Medicine/Society and Medicine

"Daughter from California" syndrome is a phrase used in the medical profession to describe a situation in which a long-lost relative arrives at the hospital at which a dying elderly relative is being treated, and insists that the medical team pursue aggressive measures to prolong the patient's life, or otherwise challenges the care the patient is being given. In his 2015 book The Conversation: A Revolutionary Plan for End-of-Life Care, American doctor Angelo Volandes ascribes this to "guilt and denial," "not necessarily what is best for the patient."

The "daughter from California" is often described as angry, articulate and informed.

Medical professionals say that because the "daughter from California" has been absent from the life and care of the elderly patient, they are frequently surprised by the scale of the patient's deterioration, and may have unrealistic expectations about what is medically feasible. They may feel guilty about having been absent, and may therefore feel motivated to reassert their role as an involved caregiver.

The phrase was first documented by a collective of gerontologists in a 1991 case report published in the Journal of the American Geriatrics Society, titled "Decision Making in the Incompetent Elderly: 'The Daughter from California Syndrome'". In the paper, Molloy and colleagues presented strategies intended to help medical staff deal with the difficult family members of mentally incompetent patients.

In California, the "daughter from California" is known as the "daughter from New York".

🔗 Medicine 🔗 Dance

Dancing mania (also known as dancing plague, choreomania, St. John's Dance and St. Vitus's Dance) was a social phenomenon that occurred primarily in mainland Europe between the 14th and 17th centuries. It involved groups of people dancing erratically, sometimes thousands at a time. The mania affected men, women, and children who danced until they collapsed from exhaustion. One of the first major outbreaks was in Aachen, in the Holy Roman Empire, in 1374, and it quickly spread throughout Europe; one particularly notable outbreak occurred in Strasbourg in 1518, also in the Holy Roman Empire.

Affecting thousands of people across several centuries, dancing mania was not an isolated event, and was well documented in contemporary reports. It was nevertheless poorly understood, and remedies were based on guesswork. Often musicians accompanied dancers, due to a belief that music would treat the mania, but this tactic sometimes backfired by encouraging more to join in. There is no consensus among modern-day scholars as to the cause of dancing mania.

The several theories proposed range from religious cults being behind the processions to people dancing to relieve themselves of stress and put the poverty of the period out of their minds. It is speculated to have been a mass psychogenic illness, in which physical symptoms with no known physical cause are observed to affect a group of people, as a form of social influence.

🔗 Medicine 🔗 Physiology 🔗 Scuba diving 🔗 Physiology/neuro

The diving reflex, also known as the diving response and mammalian diving reflex, is a set of physiological responses to immersion that overrides the basic homeostatic reflexes, and is found in all air-breathing vertebrates studied to date. It optimizes respiration by preferentially distributing oxygen stores to the heart and brain, enabling submersion for an extended time.

The diving reflex is exhibited strongly in aquatic mammals, such as seals, otters, dolphins, and muskrats, and exists as a lesser response in other animals, including adult humans, babies up to 6 months old (see infant swimming), and diving birds, such as ducks and penguins.

The diving reflex is triggered specifically by chilling and wetting the nostrils and face while breath-holding, and is sustained via neural processing originating in the carotid chemoreceptors. The most noticeable effects are on the cardiovascular system, which displays peripheral vasoconstriction, slowed heart rate, redirection of blood to the vital organs to conserve oxygen, release of red blood cells stored in the spleen, and, in humans, heart rhythm irregularities. Although aquatic animals have evolved profound physiological adaptations to conserve oxygen during submersion, the apnea and its duration, bradycardia, vasoconstriction, and redistribution of cardiac output occur also in terrestrial animals as a neural response, but the effects are more profound in natural divers.

🔗 Technology 🔗 Medicine

The Corsi–Rosenthal Box, also called a Corsi–Rosenthal Cube or a Comparetto Cube, is a design for a do-it-yourself air purifier that can be built comparatively inexpensively. It was designed during the COVID-19 pandemic with the goal of reducing the levels of airborne viral particles in indoor settings.

🔗 United States 🔗 International relations 🔗 Disaster management 🔗 Medicine 🔗 Viruses 🔗 Canada 🔗 Death 🔗 Agriculture 🔗 Mexico

The 2009 flu pandemic or swine flu was an influenza pandemic that lasted from January 2009 to August 2010, and the second of the two pandemics involving H1N1 influenza virus (the first being the 1918–1920 Spanish flu pandemic), albeit a new strain. First described in April 2009, the virus appeared to be a new strain of H1N1, which resulted from a previous triple reassortment of bird, swine, and human flu viruses further combined with a Eurasian pig flu virus, leading to the term "swine flu". According to WHO, the laboratory confirmed death toll is more than 18,036. Meanwhile, some studies estimated that 11 to 21 percent of the global population at the time – or around 700 million to 1.4 billion people (out of a total of 6.8 billion) – contracted the illness. This was more than the number of people infected by the Spanish flu pandemic, but only resulted in about 150,000 to 575,000 fatalities for the 2009 pandemic. A follow-up study done in September 2010 showed that the risk of serious illness resulting from the 2009 H1N1 flu was no higher than that of the yearly seasonal flu. For comparison, the WHO estimates that 250,000 to 500,000 people die of seasonal flu annually.

Unlike most strains of influenza, the Pandemic H1N1/09 virus does not disproportionately infect adults older than 60 years; this was an unusual and characteristic feature of the H1N1 pandemic. Even in the case of previously very healthy people, a small percentage develop pneumonia or acute respiratory distress syndrome (ARDS). This manifests itself as increased breathing difficulty and typically occurs three to six days after initial onset of flu symptoms. The pneumonia caused by flu can be either direct viral pneumonia or a secondary bacterial pneumonia. A November 2009 New England Journal of Medicine article recommended that flu patients whose chest X-ray indicates pneumonia receive both antivirals and antibiotics. In particular, it is a warning sign if a child (and presumably an adult) seems to be getting better and then relapses with high fever, as this relapse may be bacterial pneumonia.